click here for details           Cosopt  (U.S.N.L.M.)
Dosing 1 drop bid
Chem Specs dorzolamide 2%, timolol 0.5%
Quantities 5, 10ml
Cost 22.00/10ml (generic)
Class carbonic anhydrase inhibitor, beta blocker
Action Inhibition of carbonic anhydrase II slows bicarbonate formation reducing sodium and fluid transport.
Beta-receptor blockers reduce aqueous production at the non-pigmented ciliary epithelium.
Usage Indicated for the reduction of elevated IOP in patients with open-angle glaucoma
or ocular hypertension who are insufficiently responsive to beta-blockers alone.
Sulfonamides can cause hypersensitivity fatalities, Stevens-Johnson syndrome, toxic epidermal
necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia. Beta blockers have caused
severe respiratory reactions and cardiac reactions, including death due to bronchospasm in patients
with asthma, and rarely death in association with cardiac failure.
Contraindications Bronchial asthma, COPD, sinus bradycardia, second or third degree atrioventricular block,
overt cardiac failure, cardiogenic shock, hypersensitivity to any component of this product.
Pediatric use > 2 years
Pregnancy Category C
BAK preserved. Preservative-free single dose units available. (Cosopt PF)
Cosopt PF is not generic and cost per 60 unit package is around $160.00.