click here for details           Maxitrol Ointment  (U.S.N.L.M.)
Dosing 1/2" tid or qid. Taper
Chem Specs neomycin 0.35%, polymyxin B, dexamethasone 0.1%
Quantities 3.5 gm tube
Cost 20.00  generic
Class aminoglycoside, cationic detergent, corticosteroid
Action Aminoglycosides inhibit bacterial protein synthesis so are active against
gram-positive species.  Polymyxins bind to bacterial cell membrane
increasing permeability so are active against gram-negative species.
Corticosteroids inhibit arachidonic acid release .
Activity Active against Staphylococcus aureus, Escherichia coli, Haemophilus
influenzae, Klebsiella/Enterobacter species, Neisseria species, and
Pseudomonas aeruginosa
Usage Indicated for ocular surface and palpebral conjunctival inflammation
where a risk of bacterial infection exists.
Inadequate coverage against: Serratia marcesens and streptococci,
including Streptococcus pneumoniae. Hypersensitivity to neomycin is
common. Glaucoma risk with extended use.
Contraindications Acanthamoeba, most viral, mycobacterial, and fungal disease.
Hypersensitivity to this or other sulfonamides or corticosteroids.
Pediatric use > 2 years
Pregnancy Category C
Commonly used for staph blepharitis when cost is a concern.
Generic: Neo Poly Dex Ointment,  NPD Ophthalmic Ointment