click here for details           Timoptic  (U.S.N.L.M.)
Dosing Initial: 1 drop 0.25% bid; monitor and adjust. 1 drop qAM 0.25% or 0.50% is common.
Chem Specs timolol maleate 0.25, 0.5%
Quantities 5, 10, 15ml, 0.2 mL unit doses.
Cost 7.00 / 5ml  generic
Class Non-selective beta-adrenergic receptor blocker.
Action Reduces aqueous formation by blocking beta2 receptors on nonpigmented ciliary epithelium.
Usage Indicated in the treatment of elevated intraocular pressure in patients with
ocular hypertension or open-angle glaucoma. Usually result is 25% IOP reduction
10 to 20% do not respond adequately to beta-blockers.
Use in normal tension glaucoma remains questionable.
Contraindications Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia,
second or third degree atrioventricular block, overt cardiac failure, cardiogenic
shock or hypersensitivity to any component of the product.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Category C
Available as preservative free 0.2 mL "Ocudose" unit doses,
otherwise BAK preserved.
Common U.S. brand name Istalol. (B&L)
Timolol hemihydrate (Betimol $133.00) demonstated to have the same efficacy as the maleate form.