click here for details           Tobradex  (U.S.N.L.M.)
Dosing 1 or 2 drops q4-6 hrs, q2hr 1st 24 or 48hr if needed, taper
Chem Specs tobramycin 0.3%   dexamethasone 0.1%
Quantities 2.5, 5, 10ml
Cost 55.00/5ml    generic
Class aminoglycoside corticosteroid
Action Aminoglycosides prevent bacterial protein synthesis. Corticosteroids
inhibit arachidonic acid release.
Activity Active against a wide variety of gram-negative and gram-positive bacteria
includings some penicillin-resistant and gentamicin-resistant strains .
Usage Indicated for steroid-responsive inflammatory conditions where superficial
bacterial infection or a risk of bacterial infection exists.
Glaucoma and cataract risk with extended use.
Contraindications Acanthamoeba, most viral, mycobacterial, and fungal disease. Hypersensitivity
to this or other aminoglycosides, corticosteroids, or any components of the
Pediatric use > 2 years
Pregnancy Category C
Exercise caution with severe or unresponsive keratitis as
steroids will exacerbate many nonbacterial infections.