click here for details           Tobradex ST  (U.S.N.L.M.)
Dosing 1 or 2 drops q4-6 hrs, q2hr 1st 24 or 48hr if needed, taper
Chem Specs tobramycin 0.3%   dexamethasone 0.05%
Quantities 2.5, 5, 10ml
Cost 220.00/5ml
Class aminoglycoside corticosteroid
Action Aminoglycosides prevent bacterial protein synthesis. Corticosteroids
inhibit arachidonic acid release.
Activity Active against a wide variety of gram-negative and gram-positive bacteria
includings some penicillin-resistant and gentamicin-resistant strains .
Usage Indicated for steroid-responsive inflammatory conditions where superficial
bacterial infection or a risk of bacterial infection exists.
(Used up to one week on posterior blepharitis.)
Glaucoma and cataract risk with extended use.
Contraindications Acanthamoeba, most viral, mycobacterial, and fungal disease. Hypersensitivity
to this or other aminoglycosides, corticosteroids, or any components of the
medication.
Pediatric use > 2 years
Pregnancy Category C
Addition of xanthan gum allows reduction of dexamethasone concentration
to 0.05% without reducing efficacy.