Zirgan  (U.S.N.L.M.)
Dosing/ Herpes Simplex 1 gt 5 times per day (q3hr while awake) until the corneal ulcer heals,
then 1 drop 3 times per day for 7 days.
Chem Specs 0.15% ganciclovir gel
Quantities 5 gm tube
Cost 463.00 / 5 gm tube
Class Ganciclovir is a guanine analogue.
Action Activated form inhibits viral DNA synthesis.
Activity Ganciclovir is active against most species in the herpesvirus family.
Usage Indicated for the treatment of acute herpetic keratitis (dendritic ulcers).
(Two thirds of early Acanthamoeba keratitis are misdiagnosed as HSV.)
Contraindications Hypersensitivity to Ganciclovir or any included ingredients.
Pediatric use > 2 years
Pregnancy No adequate and well-controlled studies in pregnant women. Teratogenic in
animals when 10,000 to 17,000 times the human ophthalmic dose is administered.
No adequate and well-controlled studies in pregnant women. Teratogenic in animals when 10,000 to 17,000 times the human ophthalmic dose is administered.
0.0075% BAK preserved.    Does not require refrigeration.
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