click here for details           Zylet  (U.S.N.L.M.)
Dosing q1-2hr in first 24-48 hrs if needed, then q4-6hr x 2 wks.   Taper.
For chronic lid margin disease "pulse" 1 week qid dosing to treat recurrences.
Chem Specs Tobramycin 0.3%, Loteprednol etabonate 0.5%
Quantities 2.5, 5, 10ml
Cost 250.00/5ml
Class aminoglycoside, ester steroid
Action Aminoglycosides prevent bacterial protein synthesis. Corticosteroids
inhibit arachidonic acid release.
Activity Active against a wide variety of gram-negative and gram-positive bacteria
including some penicillin-resistant and gentamicin-resistant strains.
Usage Indicated for steroid-responsive inflammatory conditions where superficial
bacterial infection or a risk of bacterial infection exists.
Off label usage for blepharitis related dry eye and GPC (see literature for details).
Contraindications Acanthamoeba, most viral, mycobacterial, and fungal disease. Hypersensitivity
to this or other aminoglycosides, corticosteroids, or any components of the
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Category C