| Azopt (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | 1 drop tid | |
| Chem Specs | brinzolamide 1% | |
| Quantities | 10, 15ml | |
| Cost | 360.00 / 10ml | |
| Class | carbonic anhydrase inhibitor | |
| Action | Inhibition of carbonic anhydrase II in the ciliary processes presumably slows the formation of bicarbonate with subsequent reduction in sodium and fluid transport. Inhibition of carbonic anhydrase II in the ciliary processes presumably slows the formation of bicarbonate with subsequent reduction in sodium and fluid transport. |
|
| Usage | Indicated for elevated IOP of ocular hypertension or open-angle glaucoma. | |
| Brinzolamide is a sulfonamide but one retrospective study1 suggested that topical CIA's can be safely used despite a patient reported history of "sulfa alergy". Use cautioned as sensitization may occur when sulfonamides are readministered. Brinzolamide is a sulfonamide but one retrospective study1 suggested that topical CIA's can be safely used despite a patient reported history of "sulfa alergy". Use cautioned as sensitization may occur when sulfonamides are readministered. |
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| Contraindications | Hypersensitivity to any of the product contents. | |
| Pediatric use | Effectiveness in pediatric patients has not been established. | |
| Pregnancy | Category C. There are no adequate studies in pregnant women. | |
| Less sting than dorzolamide 2% solution. May be used concomitantly with other IOP lowering topicals. 0.01% BAK preserved. Less sting than dorzolamide 2% solution. May be used concomitantly with other IOP lowering topicals. 0.01% BAK preserved. |
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