| Besivance (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | Invert and shake bottle; one drop tid for 7 days For more severe infections: use hourly dosing while awake; include a broad spectrum antibiotic ointment at bedtime. |
|
| Chem Specs | besifloxacin 0.6% suspension | |
| Quantities | 5ml in 7ml bottle | |
| Cost | 241.45/5ml | |
| Class | dual-halogenated chlorofluoroquinolone - 4th generation fluoroquinolone | |
| Action | Bactericidal via inhibition of DNA gyrase. | |
| Active against many gram positive organisms including MRSA/MRSE, as well as gram negatives including Pseudomonas aeruginosa. Resistance profile similar to compounded Vancomycin. |
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| Usage | Indicated for the treatment of bacterial conjunctivitis. | |
| Contraindications | Hypersensitivity to any of the ingredients in the formulation. | |
| Pediatric use | > age 1 | |
| Pregnancy | There are no available human data for the use of BESIVANCE during pregnancy. Administration to rats did not produce adverse embryofetal or offspring effects. |
|
| BAK preserved. | ||
| Suspension, should be shaken. DuraSite vehicle prolongs contact time. Possible anti-inflammatory action has been suggested. |
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