| Cequa (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | 1 drop bid 12 hours apart | |
| Chem Specs | cyclosporine 0.09% | |
| Quantities | 0.25 ml vials, (60 vials per box) | |
| Cost | 624.00 (box of 60) See Canadian information below. | |
| Class | peptide immunosuppressant | |
| Action | Calcineurin inhibitor, modulates T-cell function. | |
| Usage | Indicated to increase tear production where tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. |
|
| Adverse Reactions | Pain on instillation (22%) and conjunctival hyperemia (6%). | |
| Contraindications | Active ocular infections and hypersensitivity to any ingredients in the formulation. | |
| Pediatric use | Safety and efficacy not established in pediatric patients below the age of 18. | |
| Pregnancy | Oral administration to rats at the equivalent to 3200x human ophthalmic dose is teratogenic. | |
| Can be used concomitantly with artificial tears, allowing 15 minutes between products. | ||
| Micelles (aggregates of surfactant molecules) said to aid cell penetration. Canadian generic: www.mapleleafmeds.com $64.00/30vials |
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