|           Ciloxan Ointment  (U.S.N.L.M.) | |
|---|---|
| Dosing/ Corneal Ulcer | 1/2" ribbon qhs to supplement daytime drop therapy |
| Dosing/ Conjunctivitis | 1/2" ribbon tid x 2 days, then bid x 5 days |
| Chem Specs | ciprofloxacin HCL 0.3% |
| Quantities | 3.5 gram |
| Cost | 277.77 |
| Class | second generation fluoroquinolone |
| Action | Binds bacterial DNA gyrase |
| Activity | Active against broad spectrum of gram positive and negative organisms. |
| Usage | Indicated for the treatment of corneal ulcers and conjunctivitis. Effective against Pseudomonas. |
| Increasing gram-positive resistance found in bacterial keratitis. Up to 85% resistance for coagulase-negative Staphyloccus. |
|
| Contraindications | Quinolone hypersensitivity |
| Pediatric use | Safety and effectiveness below the age of two years have not been established. |
| Pregnancy | There are no adequate and well controlled studies in pregnant women. Rat and rabbit studies have not produced teratogenicity. |