| Garamycin (U.S.N.L.M.) | |
|---|---|
| Dosing/ | 1 or 2 drops q 4 hr; if severe, 2 drops hourly while in severe stage. |
| Chem Specs | gentamicin 0.3% |
| Quantities | 5 ml, 15ml |
| Cost | 26.79 (generic) |
| Class | Aminoglycoside |
| Action | Prevents bacterial protein synthesis by binding to s30 ribosomal subunit. |
| Activity | Active against a wide variety of gram-negative and gram-positive bacteria including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, Enterobacter aerogenes Escherichia coli; Haemophilus influenzae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens. |
| Usage | Indicated in the treatment of external infections of the eye and adnexa. |
| Increasing resistance from community-acquired infections including Pseudomonas spp., Staphylococcus aureus and other Staphylococcus spp. and others. Aminoglycoside toxicity possible with pre-sensitized pts. or with extended use. |
|
| Contraindications | Known hypersensitivity to any of its components. |
| Pediatric use | > 2 months |
| Pregnancy | There are no adequate and well-controlled studies in pregnant women. Systemic use can cause permanent fetal hearing loss. 500x the human ophthalmic dose in Pregnant rats causes depresesses body weight in newborns. |
| Consider using a newer fluoroquinolone. | |
| Also available as 0.3%, 3.5g ointment. |