Homatropine  (U.S.N.L.M.)
Dosing  (uveitis/iritis) 1 or 2 drops 5% up to q3hr or q4hr   (bid to qid common practice)
1 drop 2% bid or tid for children
Dosing (cycloplegia) Instill 1 or 2 drops 2%, repeat in 5 to 10 min if nec.
Chem Specs homatropine HBr 2%, 5%
Quantities 5ml
Cost 33.00/5ml
Class anticholinergic
Action Competitive antagonist for the muscarinic acetylcholine receptor.
Usage Indicated for cycloplegic refraction or for pupil dilation in acute inflammatory
conditions of the iris and uveal tract.
Increased susceptibility in infants, young children, and in children with blond hair,
blue eyes, Down's syndrome, spastic paralysis, or brain damage.
Contraindications Untreated narrow-angle glaucoma, or untreated anatomically narrow angles,
or hypersensitivity to any component of the preparation.
Pediatric use Homatropine should not be used during the first 3 months of life due to a possible
association between the cycloplegia produced and the development of amblyopia.
Pregnancy Category C.  Animal reproduction studies have not been conducted.
Peak mydriasis 40-60 min. Peak cycloplegia 30-60 min. Recovery 1-3 days.
Roughly 1/10 as potent as atropine. Nasolacrimal pressure recommended.
Isopto Homatropine discontinued by Alcon 2013. Homatropine HBr 5% available
from Altaire.
    N.L.M. DailyMed page for Homatropine