| Phenylephrine (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | 1 or 2 drops of 2.5% or 10% every 3 to 5 minutes. Maximum of 3 drops per eye. Use 2.5% for pediatric patients less than 1 year of age. |
|
| Chem Specs | phenylephrine 2.5%, 10% | |
| Quantities | 10ml,15ml (2.5%). 5ml, (10%) | |
| Cost | 110.00/15ml | |
| Class | alpha-1 adrenergic receptor agonist | |
| Action | The α-adrenergic effect constricts the radial muscle of the iris and ophthalmic blood vessels | |
| Usage | Pupil dilation. Adjunctive IOP reduction. | |
| Maximal mydriasis occurs in 20-90 minutes with recovery after 3 to 8 hours. | ||
| Contraindications | Narrow angle glaucoma. 10% phenylephrine is contraindicated in patients with hypertension, or thyrotoxicosis. 2.5% may be used with caution for these patients. |
|
| Warnings | Use caution where retinal vasculature is compromised. Systemic absorption can increase blood pressure and heart rate. |
|
| Pediatric use | 10% phenylephrine is contraindicated in pediatric patients less than 1 year of age. 2.5% may be used with caution for these patients. |
|
| Pregnancy | Category C. Fetal harm has been demonstrated in animal studies. | |