| Pred-G Ointment Ointment (U.S.N.L.M.) | ||
|---|---|---|
| Dosing | 1/2" ribbon, one to three times daily | |
| Chem Specs | gentamicin sulfate equivalent to 0.3%, prednisolone acetate 0.6% | |
| Quantities | 3.5 gm tube | |
| Cost | 175.00 | |
| Class | aminoglycoside, corticosteroid | |
| Action | Aminoglycosides inhibit bacterial protein synthesis. Corticosteroids inhibit arachidonic acid release . |
|
| Activity | Active against a variety of aerobic bacteria including Pseudomonas aeruginosa, Haemophilus influenzae, Staph aureus, and Serratia marcescens. Active against a variety of aerobic bacteria including Pseudomonas aeruginosa, Haemophilus influenzae, Staph aureus, and Serratia marcescens. |
|
| Usage | Indicated for ocular surface and palpebral conjunctival inflammation where a risk of bacterial infection exists. |
|
| Glaucoma and cataract risk with extended use. | ||
| Contraindications | Acanthamoeba, most viral, mycobacterial, and fungal disease. Hypersensitivity to any component. |
|
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. | |
| Pregnancy | Systemic use of gentamycin during pregnancy can cause fetal hearing loss. Prednisolone is teratogenic in mice at 1-10 times the human ocular dose. |
|
| Exercise caution with severe or unresponsive keratitis as steroids will exacerbate many nonbacterial infections. |
||