Rocklatan  (U.S.N.L.M.)
Dosing qpm
Chem Specs netarsudil 0.02%,    latanoprost 0.005%
Quantities 2.5ml,
Cost 361.60
Class     netarsudil:           Rho Kinase inhibitor.
    latanoprost:    Prostaglandin F2α analogue (prodrug).
Usage 30% reduction in IOP achieved in 60% of users.

Hypersensitivity to Xalantan or any other ingredient in the product.


Latanoprost hypersensitivity
Side Effects

Mild conjunctival hyperemia occurs in 50% to 60%, but is consistently observed in only
10% and so is considered "well tolerated". Corneal epithelial macrocysts, small conjunctival
hemorrhages, and cornea verticillata(20%) which resolve on discontinuation.


Generally less hyperemia, less pigmentation of iris, periorbital tissue (eyelid), and eye-
lashes than Lumigan. Possible cystoid macular edema in pseudophakes and aphakes.
May exacerbated iritis/uveitis. Possible reactivation of herpes simplex and zoster. Dry
eye-like surface inflammation observed in mice.1 Avoid with inflammatory glaucomas
and surface eye disease.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Latanoprost has been used in children as young as 5 yrs without notable problems.2
Pregnancy Category C. Embryofetal lethality in rabbits at 80x the normal human dose but not at 15x.
0.015% BAK may be absorbed by contact lenses. Contact lenses should be removed
prior to administration of the solution. Lenses may be reinserted 15 minutes following
1. Yang Y, et al. Invest Ophthalmol Vis Sci. July 2018, Vol.59, 3375-3384
2. Younus M, et al. Am J Ophthalmol. 2018;doi:10.1016/j.ajo.2018.08.039.
    N.L.M. DailyMed page for Pilocarpine