Tim-Brim-Dor-Lat™PF   (U.S.N.L.M.)
Dosing q.p.m. This is the PM arm of the "Triple/Quad, AM - PM pairing".
It is intended for use in unison with the triple "AM combination"1.
Chem Specs timolol 0.5%,  brimonidine 0.15%,   dorzolamide 2.0%,   latanoprost 0.005%
Quantities 5ml,
Cost 152.00
Class timolol:           Non-selective beta-adrenergic receptor blocker.
brimonidine:   Relatively selective alpha-2 agonist.
dorzolamide:   Carbonic anhydrase inhibitor
latanoprost:    Prostaglandin analog (prodrug)
Usage The preservative-free, single container preparation can reduce surface toxicity and
enhance compliance.

Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia,
second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock.
Numerous additional cautions listed here.


neonates and infants (under the age of 2 years)
Vascular insufficiency cautions listed here.


Sulfonamide hypersensitivity.


Latanoprost hypersensitivity
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Pregnancy Category C   Embryofetal lethality shown in rats and rabbits at clinically relevant doses.
1. The "AM combination" Tim-Brim-Dor™ is similar but lacks latanaprost (daily dosing).
Bottle with one way valve requires refrigeration.
Individual drugs are FDA approved but the combination is not.