| Tim-Dor-Lat™PF (U.S.N.L.M.) | |
|---|---|
| Dosing | q.p.m. Prescribed as the PM arm in unison with Cosopt (AM)1. |
| Chem Specs | timolol 0.5%, dorzolamide 2.0%, latanoprost 0.005% |
| Quantities | 5ml, |
| Cost | 130.00 |
| Class |
timolol: Non-selective beta blocker. dorzolamide: Carbonic anhydrase inhibitor latanoprost: Prostaglandin analog (prodrug) |
| Usage | The preservative-free, single container preparation can reduce surface toxicity and enhance compliance. |
| Contraindications |
timolol
Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock. Numerous additional cautions listed here.
dorzolamide Sulfonamide hypersensitivity.
latanoprost
Latanoprost hypersensitivity |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. |
| Pregnancy | Category C Embryofetal lethality shown in rats and rabbits at clinically relevant doses. |
| 1. The "AM combination" Cosopt is similar but lacks latanaprost (daily dosing). | |
| Bottle with one way valve requires refrigeration. Individual drugs are FDA approved but the combination is not. |