| Timoptic XE gel (U.S.N.L.M.) | |
|---|---|
| Dosing | 1 drop 0.25% qAM or 0.5% (for more highly pigmented eyes) |
| Chem Specs | timolol maleate 0.25, 0.5% |
| Quantities | 2.5, 5ml |
| Cost | 212.79/5ml |
| Class | Non-selective beta-adrenergic receptor blocker. |
| Action | Reduces aqueous formation by blocking beta2 receptors on nonpigmented ciliary epithelium. |
| Usage | Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Gel forms upon contact with tears. Subsequently removed by the flow of tears. | |
| Contraindications | Bronchial asthma, a history of bronchial asthma, COPD, sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock or hypersensitivity to any component of the product. |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. |
| Pregnancy | Category C. Increased fetal resorptions in rabbits with dosage 14,000 times the human dose. |
| GELRITE is a purified anionic heteropolysaccharide derived from gellan gum. BDZB preserved (benzododecinium bromide). |