Tobrex Ointment  (U.S.N.L.M.)
Dosing/ bid, tid,  (or q3-4 hr for severe disease)  then bid or tid till end.
Chem Specs tobramycin 0.3%
Quantities 3.5 gm tube
Cost 262.00
Class Aminoglycoside
Action Prevents bacterial protein synthesis (binds to ribosome s30 or s50)
Activity Active against a wide variety of gram-negative and gram-positive bacteria
includings some penicillin-resistant and gentamicin-resistant strains .
Usage Indicated in the treatment of external infections of the eye and adnexa.
Increasing resistance from community-acquired infections. Aminoglycoside
toxicity possible with pre-sensitized pts. or with extended use. Polysporin is the
usual alternative.
Contraindications Known hypersensitivity to any of its components.
Pediatric use > 2 months
Pregnancy 3 animal studies have failed to demonstrate fetal risk.
No adequate and well-controlled studies in pregnant women.
    N.L.M. DailyMed page for Tobrex Ointment         PDR page for Tobrex Ointment