Travatan  Z
Dosing 1 drop qhs    (qAM dosing is considered acceptable.)
Chem Specs travoprost 0.004%
Quantities 2.5,   5ml
Cost 164.38 (generic)      208.00 (Z formulation - see below)
Class prostaglandin analog
Action Believed to increase uveoscleral aqueous outflow.
Usage Indicated for lowering IOP with open-angle glaucoma or ocular hypertension for
those who are intolerant of other IOP lowering medications or insufficiently
responsive to another IOP lowering medication.   28% - 30% IOP reduction.
Side Effects Pigmentation of the iris, eyelid and eyelashes, and growth of eyelashes.
Possible cystoid macular edema in pseudophakes and/or aphakes.
Possible reactivation of herpes keratitis. Possible corneal thinning.
30 to 50% report ocular hyperemea. 3% discontinue use for this reason.
May exacerbate uveitis.
Contraindications Hypersensitivity to travoprost or any other ingredients in the product.
Pediatric use Below the age of 16 years not recommended due to "potential safety concerns
related to increased pigmentation following long-term chronic use".
Pregnancy Category C. Embryo-fetal lethality shown in rats with low dose subcutaneous injections.
Travatan Z uses "sofzia" preservative rather than BAK
Travatan Z replaced Travatan in 2017.
    N.L.M. DailyMed page for Travatan Z          PDR page for Travatan Z