Ultram  (U.S.N.L.M.)
Dosing: (Iritis, corneal abrasion.) 25 to 50mg every 4 to 6 hours, not to exceed 400mg daily.
May be increased to 100mg q6hr.
Chem Specs tramadol hydrochloride
Quantities Use lowest dosage for the shortest duration consistent with patient requirements.
Cost 45.54 / 60 tablets generic
Class Synthetic ÎĽ-opioid receptor agonist.
Tramadol also acts as a weak serotonin–norepinephrine reuptake inhibitor.
Action Major active metabolite desmethyltramadol(M1) activates opioid
receptors with intrinsic activity similar to morphine.
Usage Moderate to moderatly severe pain relief.
Caution Alcohol and other CNS depressants may cause additive CNS depression.
A small number of patients (1-10%)? are "ultra fast metabolizers" subject to
dangerous respiratory depression so use caution on initiation of treatment.
Contraindications Hypersensitivity to tramadol. Patients with significant respiratory depression,
severe bronchial asthma, gastrointestinal obstruction, using of monoamine
oxidase inhibitors (MAOIs) or use within the previous 14 days.
Pediatric use Contraindicated under age 12 and for postoperative use for children under 18.
Pregnancy Embryotoxic and fetotoxic in rats at doses comparable to maximum human dosage.
Schedule IV.
Pain relief usually occurs within an hour with immediate-release formulation.
    N.L.M. DailyMed page for Ultram          PDR page for Ultram