| Vevye | |
|---|---|
| Dosing | one drop bid in each eye, 12 hours apart. |
| Chem Specs | 0.1% cyclosporine ophthalmic solution |
| Quantities | 2 ml in a 5 ml bottle dropper |
| Cost | $929.00 / bottle |
| Class | calcineurin inhibitor |
| Action | selective immunomodulator (prevents T cell activation) |
| Usage | Indicated for the treatment of signs and symptoms of dry eye disease. |
| About 10% respond with ≥ 10 mm increase in Schirmer’s wetting after 29 days. | |
| Contraindications | None |
| Pediatric use | Safety and effectiveness in pediatric patients have not been established. |
| Pregnancy | There are no adequate and well-controlled studies of VEVYE administration in pregnant women. Teratogenic to rats when orally administered at 7,250 times the normal human ophthamic dose. |
| Non water vehicle EyeSol®(Perfluorohexyloctane (F6H8)) provides smaller drop size and longer on-eye residual period. Contact lenses may be inserted 15 minutes following administration. |