| Xdemvy (U.S.N.L.M.) | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dosing | One drop BID 12 hr apart for 6 weeks | ||||||||||||||||||
| Chem Specs | lotilaner 0.25% solution | ||||||||||||||||||
| Quantities | 10 mL dropper tip bottle
| Cost |
$1850 |
Class |
chloride channel inhibitor |
Action |
Prevents GABA binding in insects which prevents chloride anion passage. |
Usage |
Indicated for the treatment of Demodex blepharitis.
|
| 10% of patients report stinging on instillation. less than 2% report chalazion, |
hordeolum or punctate keratitis. Contraindications |
None |
Pediatric use |
Safety and efficacy not established in pediatric patients below the age of 18.
|
Pregnancy |
In animal reproduction studies, lotilaner did not produce malformations at clinically |
relevant doses. Teratogenicity is shown in rats at 1650x the normal human dose.
| Remove contact lenses prior to use; reinsert 15 minutes following administration. |
|