Xelpros  (U.S.N.L.M.)
Dosing 1 drop qpm (optimal),       (AM dosing is considered acceptable.)
Chem Specs latanoprost 0.005%
Quantities 2.5ml
Cost 75.63
Class prostaglandin analog (as an isopropyl ester prodrug)
Action Increased uveoscleral aqueous outflow (possibly by loosening intercellular spaces.)
28% - 30% IOP reduction
Usage Indicated for reduction of IOP in open angle glaucoma or ocular hypertension.
IOP reduction starts in 3-4 hours. Maximum effect in 8–12 hours.
Side Effects Generally less hyperemia, less pigmentation of iris, lids, and lashes than Lumigan
Possible cystoid macular edema in pseudophakes and/or aphakes. May exacerbated
iritis/uveitis. Possible reactivation of herpes simplex and zoster. Dry eye-like surface
inflammation observed in mice.1
Avoid with inflammatory glaucomas and surface eye disease.
Contraindications Hypersensitivity to Xalantan or any other ingredient in the product.
Pediatric use Safety and effectiveness in pediatric patients have not been established.
Latanaprost has been used in children as young as 5 yrs without notable problems.1
Pregnancy Category C   Embryocidal in rabbits at 80x the human dose but not at 15x.
BAK free, replaced by non ionic surfactant (potassium sorbate).
Micelle micro-emulsion delivery vehicle.
1. Younus M, et al. Am J Ophthalmol. 2018;doi:10.1016/j.ajo.2018.08.039.     N.L.M. DailyMed page for Xelpros          PDR page for Xelpros