| Z-Pak (U.S.N.L.M.) | ||
|---|---|---|
| Dosing inclusion conjunctivitis, MGD |
Two 250mg tablets the first day, then 1 tablet per day for 4 days | |
| Chem Specs | azithromycin | |
| Quantities | Z-Pak = Package of six 250mg tablets. Tri-Pak = package three 500mg tablets. Zmax = 1,000mg oral suspension. Available as 250, 500, 600mg tablets, and single dose powder packets (1 g). Also as 200mg/5ml suspension in 15, 22.5, 30ml bottle, 100mg/5ml suspension in 15ml bottle. |
|
| Cost | 31.31/6/250 (Z-Pak generic) | |
| Class | extended-spectrum macrolide | |
| Action | Blocks bacterial protein synthesis. (Binds ribosome 50s subunit.) | |
| Usage | Indicated in the treatment of sinusitis and skin structure infections. Often used in treatment of inclusion conjunctivitis. |
|
| Warnings | Use caution with known heart arrhythmias, angina, prior heart attack or chest pain. Use caution with impaired hepatic function. |
|
| Contraindications | Hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. | |
| Pediatric use | > 5 months | |
| Pregnancy | A retrospective study found association with increased incidence of miscarriage.2 Exposure during 1st trimester associated with increased risk of abortion and birth defects. |
|
| For chlamydia the current CDC recomendation: One gram in a single dose (2 tablets, 4 tablets, or suspension). Resistance is endemic in many areas. |
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